High birth weight increases mammary tumorigenesis in rats
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چکیده
منابع مشابه
Enhancement of mammary tumorigenesis by dietary selenium deficiency in rats with a high polyunsaturated fat intake.
The effect of selenium depletion on mammary tumorigenesis following dimethylbenz[a]anthracene administration was examined in female Sprague-Dawley rats that were fed different levels and types of fats. Four basal diets deficient in selenium were used: (a) 1% corn oil; (b) 5% corn oil; (c) 25% corn oil; and (d) a high saturated fat diet containing 1% corn oil and 24% hydrogenated coconut oil. Th...
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A hypothesis is presented that explains the mammary tumor-promoting effects of high fat diets on the basis of alteration in the hormonal milieu, namely the relative concentrations of circulating prolactin to estrogen. Evidence from in vivo and in vitro studies drawn from work in our laboratory and others is reviewed in light of this hypothesis. It is postulated that mammary tumor cell prolifera...
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DNA synthesis in mammary gland estimated by [3H]thymidine incorporation was significantly higher on the day of proestrus than on the second day of diestrus in 50-day-old female Sprague-Dawley rats. The percentage of progressive mammary tumors, tumor growth rate, and the number and the weight of tumors per tumor-bearing rat were significantly higher in the animals given a single i.v. injection o...
متن کاملDexamethasone therapy increases infection in very low birth weight infants.
BACKGROUND Infection is a major complication of preterm infants, resulting in increased morbidity and mortality. We recently reported the results of a multicenter trial of dexamethasone initiated at 14 or 28 days in very low birth weight (VLBW) infants who were at risk for chronic lung disease; the results showed an increase in nosocomial bacteremia in the group receiving dexamethasone. This st...
متن کاملBirth statistics of high birth weight infants (macrosomia) in Korea
PURPOSE The authors analyzed the trend from the birth-related statistics of high birth weight infants (HBWIs) over 50 years in Korea from 1960 to 2010. METHODS We used 2 data sources, namely, the hospital units (1960's to 1990's) and Statistics Korea (1993 to 2010). The analyses include the incidence of HBWIs, birth weight distribution, sex ratio, and the relationship of HBWI to maternal age....
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ژورنال
عنوان ژورنال: International Journal of Cancer
سال: 2006
ISSN: 0020-7136,1097-0215
DOI: 10.1002/ijc.21936